01 - Pat tilapia fillets dry with paper towels. Combine chili powder, cumin, smoked paprika, garlic powder, salt, and black pepper in a small bowl. Season both sides of fillets evenly with spice mixture. Drizzle with olive oil and lime juice, turning to coat.
02 - Heat a large nonstick skillet over medium-high heat. Place seasoned fillets in the hot pan and cook for 3 to 4 minutes per side until golden brown and cooked through. Remove from heat and let rest for 2 minutes. Flake into bite-sized pieces with a fork.
03 - Combine shredded cabbage, carrots, and chopped cilantro in a large bowl. Add lime juice and olive oil. Season with salt and pepper to taste. Toss thoroughly until vegetables are evenly coated.
04 - Whisk together sour cream or Greek yogurt, lime juice, hot sauce if using, and salt in a small bowl until smooth and well combined. Adjust seasoning as needed.
05 - Heat tortillas in a dry skillet over medium heat for 30 seconds per side until warm and pliable, or microwave between damp paper towels for 20 to 30 seconds.
06 - Layer a generous portion of slaw onto each warmed tortilla. Top with flaked tilapia pieces. Drizzle with crema. Garnish with sliced avocado, fresh cilantro leaves, and a squeeze of fresh lime juice.
07 - Arrange assembled tacos on a serving platter. Serve immediately while tortillas are warm and fish is hot. Offer extra lime wedges and hot sauce on the side.